Gentamicin Therapeutic Drug Monitoring: Importance in the Hospital Setting

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Therapeutic drug monitoring for gentamicin in Hospital Universiti Sains Malaysia.

We evaluated the usefulness of therapeutic drug monitoring (TDM) for gentamicin and the use of a two-point peak and trough pair concentration method to adjust its dose. Of the 194 patients included, initial concentrations were appropriate in only sixty nine. In the seventy one cases of dosage adjustments using this method, those attaining therapeutic levels increased overall from 38% to 67%. It...

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Cost evaluation of therapeutic drug monitoring of gentamicin at a teaching hospital in Malaysia

BACKGROUND Therapeutic drug monitoring (TDM) makes use of serum drug concentrations as an adjunct to decision-making. Preliminary data in our hospital showed that approximately one-fifth of all drugs monitored by TDM service were gentamicin. OBJECTIVE In this study, we evaluated the costs associated with providing the service in patients with bronchopneumonia and treated with gentamicin. ME...

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Importance of Therapeutic Drug Monitoring of Rifampicin.

Therapeutic Drug Monitoring (TDM) is a routinely practised clinical laboratory technique which aids the clinicians with a clear clinical judgement of the drug therapy and optimize the doses if necessary. Rifampicin is the most important and potent component of first line therapy of tuberculosis (TB). Several factors like age, weight, gender, doses and formulations, gastro-intestinal disorders, ...

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Therapeutic drug monitoring of gentamicin: evaluation of five nomograms for initial dosing at Al-Amiri Hospital in Kuwait.

OBJECTIVE To compare five published nomograms (Thomson guidelines, Mawer nomogram, rule of eights, Hull-Sarubbi table and Dettli method) for calculating the initial gentamicin dosage regimen in a Kuwaiti population. MATERIALS AND METHODS Based on measured peak and trough gentamicin concentrations, the elimination rate constant and volume of distribution of gentamicin were calculated for each ...

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ژورنال

عنوان ژورنال: West Indian Medical Journal

سال: 2016

ISSN: 0043-3144

DOI: 10.7727/wimj.2015.603